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Anti-InflammaLox Herbal anti inflammatory

Price
$27.90
SKUxymo-salox
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Anti-InflammaLox contains ingredients backed by years of use in traditional herbal medicine, as well as by published research in peer-reviewed journals. Boswellia serrata, white willow bark and bioflavonoids have all been shown to possess good anti-inflammatory and analgesic properties through the inhibition of COX-2 and 5-LOX enzymes. The proprietary bioflavonoid blend provides antioxidant protection against damage to soft tissue.
* Anti-inflammatory
* Analgesic
* Antioxidant Support

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Dosing
Effectiveness appears to be dependent upon dose and
length of treatment with relief of discomfort at a higher
dose and over a period of time.

Two capsules, two or more times a day have been reported to be
effective.

Salicin (White Willow Bark, Salix alba) contains salicylates, tannins and flavonoids. Decoctions of the bark have
been used to treat pain, fever and headaches for approximately 2000 years. The role of salicylates in inflammation
and pain management is well-documented in medicine as white willow bark was the forerunner of aspirin.[1] In studies
willow bark extract strongly prevented PGE2 and cytokine release.[2] A 2007 systemic review of the literature
found moderate evidence for short-term improvements in pain with daily doses standardized to 120 mg or 240 mg
salicin.[3]
5•Loxin®, a standardized Boswellia serrata extract enriched to 30% 3-acetyl-11-keto-b-boswellic acid (AKBA), is
ten times more concentrated than ordinary boswellia. Boswellia is an ayurvedic herb whose principle constituents
boswellic acid and alpha-boswellic acid may maintain healthy leukotriene metabolism by reducing the activity of
the enzyme 5-lipoxygenase.[4] Matrix metalloproteinase (MMP), a class of enzymes that selectively hydrolyze peptide
bonds and degrade structural proteins, play a crucial role in the degradation of joint tissues. 5•Loxin® shows
significant inhibition against several MMP’s. It prevents formation of human recombinant TNFa inducible MMPs,
responsible for cartilage degradation and inflammatory mediators of apoptosis and adhesion molecules including
VCAM-1 and ICAM-1.[5] Various randomized, double-blind, placebo-controlled, crossover studies have demonstrated
the efficacy of boswellia.[6,7,8]
Metabolism of Salicin: An oral dose of salicin is rapidly and completely metabolized to mostly salicylic acid.[9] After
biotransformation to salicin in the GI tract, B-glucuronidase activity and hydrolysis covert salicin to saligenin.
Saligenin is further converted to salicylic acid in the liver by the cytochrome P- 450 system. After an oral dose (240
mg) was given to healthy volunteers, the Tmax was less than two hours and Cmax was 1.2 mg/L, respectively.[10]
Salicylic acid is eliminated in urine as salicyluric acid.[10]
BerryVin™, a bioflavonoid-rich, high ORAC berry powder containing blueberries, blackberries, strawberries, and
cranberries, along with grape and pomegranate extracts provides strong antioxidant support of soft tissues. The
bioflavonoids may act synergistically to inhibit cycloxygenase, lipoxygenase and phospholipase.[11]
Clinical Applications
• Anti-inflammatory
• Analgesic
• Antioxidant Support
Each of the ingredients in this exclusive formula is backed by years of use in
traditional herbal medicine, as well as by published research in peer-reviewed
journals. Boswellia serrata, white willow bark and bioflavonoids have all been
shown to possess good anti-inflammatory and analgesic properties through the
inhibition of COX-2 and 5-LOX enzymes. The proprietary bioflavonoid blend
provides antioxidant protection against damage to soft tissue.

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