Cyrex Labs is an advanced clinical laboratory focusing on mucosal, cellular, and humoral immunology and specializing in antibody arrays for complex thyroid, gluten, and other food-associated autoimmunities and related neurodysregulation. Cyrex’s Scientific Advisory Board, comprised of experts from a variety of medical and research disciplines, brings together the latest findings from medical research and the assessment needs of today’s healthcare professionals. Out of this collaboration, Cyrex develops the next generation of clinical lab testing that is required to care for present-day complex maladies.
Cyrex adheres to and surpasses the highest standards of clinical laboratory testing worldwide. A Cyrex-designed quality control criterion called The Double Assurance System (QC2™) is the standard operating procedure at Cyrex Laboratories. In fact, Cyrex’s proprietary QC2™ method enhances the reproducibility, specificity, and sensitivity of all Cyrex arrays. Only Cyrex tests contain the accuracy enhancements provided by The Double Assurance System.
Befroe ordering please consider the following:
• Patient has been clear of immunosuppressant AND/OR corticosteroid drugs for at least 60 days.
• Patient has had timely and adequate antigen exposure in order to measure antibody responses.
Q: Are there any medications, foods, conditions, or other factors that could interfere with the results of a Cyrex test?
A: Yes. While Cyrex is unable to provide an exhaustive answer to this question due to the interactive complexities and varieties of medications and patient circumstances, the following has been noted:
a. Immunosuppressant and corticosteroid drugs can reduce antibody production and cause false negative results.
b. Limited assessments on the effects of aspirin, acetaminophen, and antipsychotics on Arrays 1-4 have been performed. No noticeable effects were observed.
c. Inhalers can affect the results of Cyrex's oral fluid testing (Array 1). Wait two weeks after completion of inhalant dosages before collecting the specimen.
d. Unknown cross-reactive epitopes from foods and microorganisms may stimulate the antibody production in the absence of a true antigen. Cyrex has already developed Array 4 in order to recognize the most common antigens in this regard.
e. A gluten-free diet can cause false negative results on gluten protein/peptide tests.
f. Certain conditions, such as ileal pouch surgery, may cause a false positive celiac serology.1
1. Lian L, Remzi FH, Kiran RP, Fazio VW, Shen B. Clinical implication of false-positive celiac serology in patients with ileal pouch. Dis Colon Rectum. 2010 Oct; 53(10):1446-1451.