amni® original formula
A Dietary Supplement
90 Vegetarian Capsules
More than any other tissue in the body, the ocular lens and retina are continually exposed to oxygen and intense light radiation. Both light and oxygen can create free radicals that play havoc with lipids in the membranes of visual cells. Experts believe that the uncontrolled generation of free radicals in the eyes can ultimately lead to macular degeneration and cataracts. Therefore, ocular tissues rely on a strong antioxidant defense system to protect them from free radical damage. OcuTone was formulated to provide a comprehensive combination of antioxidant nutrients that research has found to be important for proper eye nutrition.
OcuTone includes nutritionally meaningful amounts of lutein, betacarotene, antioxidant vitamins, the trace elements zinc and selenium, the cellular antioxidants glutathione and N-Acetyl-L-Cysteine, the amino acid taurine, and potent flavonoids from bilberries and grape seeds. Lutein. Lutein is a carotenoid similar to beta-carotene. Recent research has shown that lutein is the major eye pigment of the outer retina. Lutein is especially concentrated in the rods, which are the visual cells of the retina that are responsible for black and white vision in the dark. The rods contain complex membranes rich in polyunsaturated fatty acids that are especially susceptible to lipid peroxidation and free radical damage. Lutein is a potent antioxidant, and researchers believe that the rods require it to protect themselves from light-induced freeradical damage.
Lutein occurs naturally in the diet, especially in dark green leafy vegetables, broccoli and kale. Most people derive about 1 to 2 mg of lutein daily from their diets. Epidemiological studies have shown that daily lutein intakes of 5 to 15 mg may be more appropriate for maintaining normal eye function during aging. As a result, OcuTone was formulated to provide 15 mg of natural lutein complex daily in three capsules. Beta-Carotene. Beta-Carotene serves at least two purposes for the eyes. It is a valuable precursor for vitamin A which functions in the rod cells as a light receptor. Beta-Carotene is also an important antioxidant in the lens and retina. OcuTone delivers 12 mg of betacarotene daily to ensure a reliable supply of this important eye nutrient. Vitamins C and E.
The healthy ocular lens is rich in the antioxidant vitamins C and E, which scavenge oxygenand light-induced free radicals. In the lens, excessive free radicals can lead to protein oxidation and polymerization, resulting in opaque, cloudy precipitates. High levels of vitamins C and E, and other natural antioxidant defense systems appear to be necessary for complete protection of the delicate, highly transparent lens proteins. OcuTone provides 500 mg of vitamin C and 400 I.U. of natural vitamin E as d-alpha-tocopherol succinate. Zinc. Zinc is essential for normal visual signal transduction in the retina. Zinc is part of many of the enzymes involved in vitamin A-dependent light reactions in the rod cells.
Moreover, zinc is an essential cofactor of superoxide dismutase, an antioxidant enzyme that removes potentially dangerous superoxide radicals in the visual cells, the lens, and other tissues. OcuTone provides 6 mg of zinc in the highly bioavailable monomethionine form. Selenium. Selenium is the essential cofactor of the antioxidant enzyme glutathione peroxidase, which is abundant in healthy eyes. Glutathione peroxidase levels, however, decline with advancing age, and experts believe that adequate selenium nutrition can help maintain normal production of this important enzyme. OcuTone provides 50 mcg of Selenium, which is roughly equivalent to the required daily amount. Glutathione and N-Acetyl-L-Cysteine. Glutathione is the essential cosubstrate for glutathione peroxidase.
To carry out its antioxidant functions, this enzyme requires a steady supply of glutathione. In addition, glutathione by itself protects the proteins in the lens from becoming insoluble and cloudy. Although well absorbed, dietary Douglas Product Data Laboratories® (continued on reverse) glutathione can not enter the cell, and exerts much of its beneficial antioxidant effects in the extracellular space. NAcetyl- L-Cysteine (NAC) easily enters the cell and is used to synthesize intracellular glutathione. NAC also appears to have antioxidant properties by itself. Many studies have shown that ocular glutathione levels decline as we age. Dietary supplementation with both glutathione and NAC may help maintain normal extracellular and intracellular glutathione levels.
Therefore, OcuTone combines a significant 50 mg of glutathione with 300 mg of NAC. Taurine. Taurine, a conditionally-essential sulfur amino acid, is the most abundant free amino acid in ocular tissues, where it may function as a membrane stabilizer, antioxidant, osmotic regulator, and neurotransmitter. Taurine is important in maintaining normal extra- and intracellular distribution of calcium. This in turn has implications forn euronal excitability and the regulation of osmotic pressure. OcuTone provides 300 mg of pure taurine. Bilberry Extract. Bilberries (Vaccinium myrtillus), a northern European cousin of North American blueberries, are a rich source of anthocyanosides, a class of flavonoids recognized for their importance in eye health. Bilberry anthocyanosides are potent antioxidants in the visual cells of the retina, and help maintain normal blood flow in the fine capillary blood vessels that nourish the eyes and other tissues.
Three capsules of OcuTone contain 60 mg of a standardized 25 % anthocyanoside extract made from ripe Swedish bilberries. Grape Seed Extract. Grape seed extract is rich in proanthocyanidins, another group of important flavonoids. Proanthocyanidins are highly regarded for their strong antioxidant properties and their role in supporting the body's capillary blood vessel system. Three capsules of OcuTone provide 50 mg of highquality European grape seed extract (from Vitis vinifera) with a minimum of 92 % proanthocyanidins.
Serving Size: 3 vegetarian capsules
Servings Per Container: 30
Amount Per Serving
Vitamin A …10,000 IU
(100% as natural beta-carotene from D. salina)
Vitamin C …500mg
(as L-ascorbic acid)
Vitamin E …400 IU
(as d-alpha tocopheryl succinate)
(as zinc monomethione**)
(as selenium amino acid complex)
N-Acetyl-L-Cysteine USP …300mg*
(as L-glutathione, reduced)
Bilberry Fruit, dried extract, …60mg*
min. 25% anthocyanosides
Grape Seed, dried extract, …50mg*
min. 92% proanthocyanidins
* Daily Value not established
** OptiZinc™ brand of methionine-bound zinc is a trademark of InterHealth Company.
Cellulose, Vegetable Stearate, Silica
As a dietary supplement, adults take 3 capsules daily with food or as directed by your healthcare professional.
KEEP OUT OF REACH OF CHILDREN.
For optimal storage conditions, store in a cool, dry place.
(35-65% relative humidity)
Tamper resistant package, do not use if outer seal is missing.