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RENUAL 60 caps by Pure Encapsulations

Mitochondrial renewal featuring Mitopure Urolithin A to power muscle function, increase cellular energy and promote healthy aging. Urolithin A is the main metabolite of ellagitannin-rich foods, such as pomegranates, black raspberries, raspberries, strawberries, walnuts and almonds. These polyphenol components are not absorbed intact into the bloodstream, but are hydrolyzed to ellagic acid in the gut, which is then metabolized by the gut microflora to form urolithin A and B. Research indicates that the ability to synthesize urolithins declines with age and depends on the gut microflora, and there is a small percentage of the population that is unable to perform this conversion at all. Research indicates that urolithin A enhances autophagy, the natural process of cellular renewal in which the body degrades and recycles cellular components, as well as mitophagy, the clearance and recycling of older and dysfunctional mitochondria. Mitochondria are the “powerhouses of the cell” and their function is fundamental to healthy aging. Efficient rejuvenation of mitochondria supports energy production and the overall health of cells. A randomized, double-blind, placebo-controlled trial involving healthy sedentary elderly subjects indicated that supplementation with urolithin A promoted mitochondrial gene expression in the muscle and fatty acid oxidation efficacy, showing support for mitochondrial biogenesis and function. Four weeks of urolithin A supplementation resulted in improved mitochondrial function comparable to a 10-week aerobic exercise regimen, as measured by decreases in plasma acylcarnitine. In animal research, urolithin A enhanced mitophagy to promote mitochondrial biogenesis and function during aging. It also improved endurance and exercise capacity in both young and age-related models of muscle decline. Supporting autophagy reduces oxidative stress and promotes healthy cytokine balance within the cells to support healthy aging. Preliminary research suggests a broad spectrum of support, including energy production, neuronal health and neurogenesis, gut barrier function, and healthy joint collagen. Urolithin A also may offer support for glucose and fat metabolism. When mice were fed a high-fat diet for 12 weeks, supplementation with urolithin A promoted healthy insulin function and lipid metabolism, and decreased adipocyte size. These results are believed to be the result of increased expression of genes targeting fatty acid beta-oxidation, adipose tissue lipolysis and insulin receptor function (Sirt1), and oxidation defenses (SOD1 and SOD2). Sirt1 is also a target of resveratrol, thereby offering support for longevity, metabolic health, and mitochondrial function. CoQ10 is a key nutrient used in the energy production pathway.

$62.20

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Description

Supplement Facts:

Amount Per Serving

Each (size 0) vegetarian capsule contains:

  • Mitopure Urolithin A……..125 mg
  • Trans-Resveratrol (from Japanese knotweed (Polygonum cuspidatum) extract (root))…….75 mg
  • Coenzyme Q10………30 mg
  • other ingredients: vegetable glycerin, vegetarian capsule (cellulose, water)
  • 2 capsules, 1-2 times daily, with or between meals
  • Kaneka Q10® is a U.S. registered trademark of Kaneka Corporation. Mitopure (proprietary Urolithin A) and the Mitopure logo are trademarks of Amazentis SA.

 

Brand

Pure Encapsulations

Pure Encapsulations vitamin supplements is one of the finest healthcare practitioner brands. There are absolutely no hidden fillers or coatings, binders, shellacs, artificial colors, fragrance or excipients in our products that would disrupt or diminish the bioavailability of any of our ingredients. Furthermore, our products are free of wheat, yeast, gluten, corn, sugar, starch, preservatives or hydrogenated oils. Pure Encapsulations manufactures their supplements in a state-of-the-art facility in Sudbury, Massachusetts. Their dedication to cleanliness is obvious from the moment our plant is entered. A large staff is dedicated full-time to the task of ensuring that our plant is impeccable.

Meet Dr. Dave

Dr. David Scheiderer MD, MBA, DFAPA, is the Chief Medical Officer and Director of Education at Integrative Psychiatry, Inc. in Sarasota, Florida and the President of Tiberius Enterprises, Inc. in Roanoke, Virginia. An accomplished clinician, educator, and lecturer, Dr. Dave has established himself as a key opinion leader in the fields of both mainstream psychiatry and functional medicine. Dissatisfied with the patient outcomes using only conventional treatments, he began treating his patients by addressing biological imbalances with lifestyle improvements, nutrition and nutraceuticals to get better outcomes. His integrative approach provided much improved results. Dr. Dave is passionate about helping the community he serves by personalizing treatments and educating the public about mental health and healthy aging. He has formulated several of our supplements and sat on the advisory board for many others, ensuring the products we carry are based on science and experience and have the best efficacy rates and highest ingredient quality available.

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